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Modaline sulfate promotes Oct4 expression and maintains self-renewal and pluripotency of stem cells through JAK/STAT3 and Wnt signaling pathways
BACKGROUND: Stem cells have been extensively explored for a variety of regenerative medical applications and they play an important role in clinical treatment of many diseases. However, the limited amount of stem cells and their tendency to undergo spontaneous differentiation upon extended propagati...
Autores principales: | Mei, Xianglin, Zhao, Hanhan, Ai, Huihan, Wang, Shuyue, Song, Zhenbo, Zheng, Lihua, Wang, Guannan, Sun, Ying, Bao, Yongli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336387/ https://www.ncbi.nlm.nih.gov/pubmed/34348786 http://dx.doi.org/10.1186/s13578-021-00669-3 |
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