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Benzylic C–H isocyanation/amine coupling sequence enabling high-throughput synthesis of pharmaceutically relevant ureas
C(sp(3))–H functionalization methods provide an ideal synthetic platform for medicinal chemistry; however, such methods are often constrained by practical limitations. The present study outlines a C(sp(3))–H isocyanation protocol that enables the synthesis of diverse, pharmaceutically relevant benzy...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336431/ https://www.ncbi.nlm.nih.gov/pubmed/34377424 http://dx.doi.org/10.1039/d1sc02049h |