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Assembly of multicyclic isoquinoline scaffolds from pyridines: formal total synthesis of fredericamycin A
The construction of an isoquinoline skeleton typically starts with benzene derivatives as substrates with the assistance of acids or transition metals. Disclosed here is a concise approach to prepare isoquinoline analogues by starting with pyridines to react with β-ethoxy α,β-unsaturated carbonyl co...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336465/ https://www.ncbi.nlm.nih.gov/pubmed/34377413 http://dx.doi.org/10.1039/d1sc02442f |