Cellular delivery of dinucleotides by conjugation with small molecules: targeting translation initiation for anticancer applications

Targeting cap-dependent translation initiation is one of the experimental approaches that could lead to the development of novel anti-cancer therapies. Synthetic dinucleoside 5′,5′-triphosphates cap analogs are potent antagonists of eukaryotic translation initiation factor 4E (eIF4E) in vitro and co...

Descripción completa

Detalles Bibliográficos
Autores principales: Kleczewska, Natalia, Sikorski, Pawel J., Warminska, Zofia, Markiewicz, Lukasz, Kasprzyk, Renata, Baran, Natalia, Kwapiszewska, Karina, Karpinska, Aneta, Michalski, Jaroslaw, Holyst, Robert, Kowalska, Joanna, Jemielity, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336483/
https://www.ncbi.nlm.nih.gov/pubmed/34377411
http://dx.doi.org/10.1039/d1sc02143e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336483/
https://www.ncbi.nlm.nih.gov/pubmed/34377411
http://dx.doi.org/10.1039/d1sc02143e

Ejemplares similares