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Cellular delivery of dinucleotides by conjugation with small molecules: targeting translation initiation for anticancer applications

Targeting cap-dependent translation initiation is one of the experimental approaches that could lead to the development of novel anti-cancer therapies. Synthetic dinucleoside 5′,5′-triphosphates cap analogs are potent antagonists of eukaryotic translation initiation factor 4E (eIF4E) in vitro and co...

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Detalles Bibliográficos
Autores principales:	Kleczewska, Natalia, Sikorski, Pawel J., Warminska, Zofia, Markiewicz, Lukasz, Kasprzyk, Renata, Baran, Natalia, Kwapiszewska, Karina, Karpinska, Aneta, Michalski, Jaroslaw, Holyst, Robert, Kowalska, Joanna, Jemielity, Jacek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336483/ https://www.ncbi.nlm.nih.gov/pubmed/34377411 http://dx.doi.org/10.1039/d1sc02143e

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