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Toward Mechanochromic Soft Material‐Based Visual Feedback for Electronics‐Free Surgical Effectors

A chromogenically reversible, mechanochromic pressure sensor is integrated into a mininvasive surgical grasper compatible with the da Vinci robotic surgical system. The sensorized effector, also featuring two soft‐material jaws, encompasses a mechanochromic polymeric inset doped with functionalized...

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Autores principales: Giordano, Goffredo, Gagliardi, Mariacristina, Huan, Yu, Carlotti, Marco, Mariani, Andrea, Menciassi, Arianna, Sinibaldi, Edoardo, Mazzolai, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336492/
https://www.ncbi.nlm.nih.gov/pubmed/34075732
http://dx.doi.org/10.1002/advs.202100418
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author Giordano, Goffredo
Gagliardi, Mariacristina
Huan, Yu
Carlotti, Marco
Mariani, Andrea
Menciassi, Arianna
Sinibaldi, Edoardo
Mazzolai, Barbara
author_facet Giordano, Goffredo
Gagliardi, Mariacristina
Huan, Yu
Carlotti, Marco
Mariani, Andrea
Menciassi, Arianna
Sinibaldi, Edoardo
Mazzolai, Barbara
author_sort Giordano, Goffredo
collection PubMed
description A chromogenically reversible, mechanochromic pressure sensor is integrated into a mininvasive surgical grasper compatible with the da Vinci robotic surgical system. The sensorized effector, also featuring two soft‐material jaws, encompasses a mechanochromic polymeric inset doped with functionalized spiropyran (SP) molecule, designed to activate mechanochromism at a chosen pressure and providing a reversible color change. Considering such tools are systematically in the visual field of the operator during surgery, color change of the mechanochromic effector can help avoid tissue damage. No electronics is required to control the devised visual feedback. SP‐doping of polydimethylsiloxane (2.5:1 prepolymer/curing agent weight ratio) permits to modulate the mechanochromic activation pressure, with lower values around 1.17 MPa for a 2% wt. SP concentration, leading to a shorter chromogenic recovery time of 150 s at room temperature (25 °C) under green light illumination. Nearly three‐times shorter recovery time is observed at body temperature (37 °C). To the best of knowledge, this study provides the first demonstration of mechanochromic materials in surgery, in particular to sensorize unpowered surgical effectors, by avoiding dramatic increases in tool complexity due to additional electronics, thus fostering their application. The proposed sensing strategy can be extended to further tools and scopes.
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spelling pubmed-83364922021-08-09 Toward Mechanochromic Soft Material‐Based Visual Feedback for Electronics‐Free Surgical Effectors Giordano, Goffredo Gagliardi, Mariacristina Huan, Yu Carlotti, Marco Mariani, Andrea Menciassi, Arianna Sinibaldi, Edoardo Mazzolai, Barbara Adv Sci (Weinh) Research Articles A chromogenically reversible, mechanochromic pressure sensor is integrated into a mininvasive surgical grasper compatible with the da Vinci robotic surgical system. The sensorized effector, also featuring two soft‐material jaws, encompasses a mechanochromic polymeric inset doped with functionalized spiropyran (SP) molecule, designed to activate mechanochromism at a chosen pressure and providing a reversible color change. Considering such tools are systematically in the visual field of the operator during surgery, color change of the mechanochromic effector can help avoid tissue damage. No electronics is required to control the devised visual feedback. SP‐doping of polydimethylsiloxane (2.5:1 prepolymer/curing agent weight ratio) permits to modulate the mechanochromic activation pressure, with lower values around 1.17 MPa for a 2% wt. SP concentration, leading to a shorter chromogenic recovery time of 150 s at room temperature (25 °C) under green light illumination. Nearly three‐times shorter recovery time is observed at body temperature (37 °C). To the best of knowledge, this study provides the first demonstration of mechanochromic materials in surgery, in particular to sensorize unpowered surgical effectors, by avoiding dramatic increases in tool complexity due to additional electronics, thus fostering their application. The proposed sensing strategy can be extended to further tools and scopes. John Wiley and Sons Inc. 2021-06-02 /pmc/articles/PMC8336492/ /pubmed/34075732 http://dx.doi.org/10.1002/advs.202100418 Text en © 2021 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Giordano, Goffredo
Gagliardi, Mariacristina
Huan, Yu
Carlotti, Marco
Mariani, Andrea
Menciassi, Arianna
Sinibaldi, Edoardo
Mazzolai, Barbara
Toward Mechanochromic Soft Material‐Based Visual Feedback for Electronics‐Free Surgical Effectors
title Toward Mechanochromic Soft Material‐Based Visual Feedback for Electronics‐Free Surgical Effectors
title_full Toward Mechanochromic Soft Material‐Based Visual Feedback for Electronics‐Free Surgical Effectors
title_fullStr Toward Mechanochromic Soft Material‐Based Visual Feedback for Electronics‐Free Surgical Effectors
title_full_unstemmed Toward Mechanochromic Soft Material‐Based Visual Feedback for Electronics‐Free Surgical Effectors
title_short Toward Mechanochromic Soft Material‐Based Visual Feedback for Electronics‐Free Surgical Effectors
title_sort toward mechanochromic soft material‐based visual feedback for electronics‐free surgical effectors
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336492/
https://www.ncbi.nlm.nih.gov/pubmed/34075732
http://dx.doi.org/10.1002/advs.202100418
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