OTUD7B Deubiquitinates LSD1 to Govern Its Binding Partner Specificity, Homeostasis, and Breast Cancer Metastasis

Genomic amplification of OTUD7B is frequently found across human cancers. But its role in tumorigenesis is poorly understood. Lysine‐specific demethylase 1 (LSD1) is known to execute epigenetic regulation by forming corepressor complex with CoREST/histone deacetylases (HDACs). However, the molecular...

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Detalles Bibliográficos
Autores principales: Gong, Zhicheng, Li, Aicun, Ding, Jiancheng, Li, Qing, Zhang, Lei, Li, Yuanpei, Meng, Zhe, Chen, Fei, Huang, Jialiang, Zhou, Dawang, Hu, Ronggui, Ye, Jing, Liu, Wen, You, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336515/
https://www.ncbi.nlm.nih.gov/pubmed/34050636
http://dx.doi.org/10.1002/advs.202004504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336515/
https://www.ncbi.nlm.nih.gov/pubmed/34050636
http://dx.doi.org/10.1002/advs.202004504

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