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Amyloid-β oligomerization monitored by single-molecule stepwise photobleaching
A major hallmark of Alzheimer’s disease is the misfolding and aggregation of the amyloid- β peptide (Aβ). While early research pointed towards large fibrillar- and plaque-like aggregates as being the most toxic species, recent evidence now implicates small soluble Aβ oligomers as being orders of mag...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336786/ https://www.ncbi.nlm.nih.gov/pubmed/32544592 http://dx.doi.org/10.1016/j.ymeth.2020.06.007 |