Concatemeric Broccoli reduces mRNA stability and induces aggregates

Fluorogenic aptamers are an alternative to established methodology for real-time imaging of RNA transport and dynamics. We developed Broccoli-aptamer concatemers ranging from 4 to 128 substrate-binding site repeats and characterized their behavior fused to an mCherry-coding mRNA in transient transfe...

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Detalles Bibliográficos
Autores principales: Rink, Marco R., Baptista, Marisa A. P., Flomm, Felix J., Hennig, Thomas, Whisnant, Adam W., Wolf, Natalia, Seibel, Jürgen, Dölken, Lars, Bosse, Jens B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336797/
https://www.ncbi.nlm.nih.gov/pubmed/34347781
http://dx.doi.org/10.1371/journal.pone.0244166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336797/
https://www.ncbi.nlm.nih.gov/pubmed/34347781
http://dx.doi.org/10.1371/journal.pone.0244166

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