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Inhibition of polo-like kinase 1 (PLK1) facilitates reactivation of gamma-herpesviruses and their elimination

Both Kaposi’s sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) establish the persistent, life-long infection primarily at the latent status, and associate with certain types of tumors, such as B cell lymphomas, especially in immuno-compromised individuals including people living wi...

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Detalles Bibliográficos
Autores principales: Biswas, Ayan, Zhou, Dawei, Fiches, Guillaume N., Wu, Zhenyu, Liu, Xuefeng, Ma, Qin, Zhao, Weiqiang, Zhu, Jian, Santoso, Netty G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336821/
https://www.ncbi.nlm.nih.gov/pubmed/34297745
http://dx.doi.org/10.1371/journal.ppat.1009764