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A mathematical modelling framework for the regulation of intra-cellular OCT4 in human pluripotent stem cells

Human pluripotent stem cells (hPSCs) have the potential to differentiate into all cell types, a property known as pluripotency. A deeper understanding of how pluripotency is regulated is required to assist in controlling pluripotency and differentiation trajectories experimentally. Mathematical mode...

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Detalles Bibliográficos
Autores principales: Wadkin, L. E., Orozco-Fuentes, S., Neganova, I., Lako, M., Parker, N. G., Shukurov, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336844/
https://www.ncbi.nlm.nih.gov/pubmed/34347824
http://dx.doi.org/10.1371/journal.pone.0254991