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A mathematical modelling framework for the regulation of intra-cellular OCT4 in human pluripotent stem cells
Human pluripotent stem cells (hPSCs) have the potential to differentiate into all cell types, a property known as pluripotency. A deeper understanding of how pluripotency is regulated is required to assist in controlling pluripotency and differentiation trajectories experimentally. Mathematical mode...
Autores principales: | Wadkin, L. E., Orozco-Fuentes, S., Neganova, I., Lako, M., Parker, N. G., Shukurov, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336844/ https://www.ncbi.nlm.nih.gov/pubmed/34347824 http://dx.doi.org/10.1371/journal.pone.0254991 |
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