miR-200 deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts

Lung adenocarcinoma, the most prevalent lung cancer subtype, is characterized by its high propensity to metastasize. Despite the importance of metastasis in lung cancer mortality, its underlying cellular and molecular mechanisms remain largely elusive. Here, we identified miR-200 miRNAs as potent su...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Bin, Chuang, Chen-Hua, Prosser, Haydn M., Fuziwara, Cesar Seigi, Chan, Claudia, Sahasrabudhe, Neil, Kühn, Maximilian, Wu, Yalei, Chen, Jingqi, Biton, Anne, Chen, Caifu, Wilkinson, John Erby, McManus, Michael T., Bradley, Allan, Winslow, Monte M., Su, Bo, He, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336896/
https://www.ncbi.nlm.nih.gov/pubmed/34301766
http://dx.doi.org/10.1101/gad.347344.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336896/
https://www.ncbi.nlm.nih.gov/pubmed/34301766
http://dx.doi.org/10.1101/gad.347344.120

Ejemplares similares