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Antibiotic prophylaxis and the gastrointestinal resistome in paediatric patients with acute lymphoblastic leukaemia: a cohort study with metagenomic sequencing analysis

BACKGROUND: Although antibiotic prophylaxis with levofloxacin can reduce the risk of serious infection in immunocompromised patients, the potential contribution of prophylaxis to antibiotic resistance is a major drawback. We aimed to identify the effects of levofloxacin prophylaxis, given to paediat...

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Detalles Bibliográficos
Autores principales: Margolis, Elisa B, Hakim, Hana, Dallas, Ronald H, Allison, Kim J, Ferrolino, Jose, Sun, Yilun, Pui, Ching-Hon, Yao, Jiangwei, Chang, Ti-Cheng, Hayden, Randall T, Jeha, Sima, Tuomanen, Elaine I, Tang, Li, Rosch, Jason W, Wolf, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336918/
https://www.ncbi.nlm.nih.gov/pubmed/34355208
http://dx.doi.org/10.1016/s2666-5247(20)30202-0