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Antibiotic prophylaxis and the gastrointestinal resistome in paediatric patients with acute lymphoblastic leukaemia: a cohort study with metagenomic sequencing analysis
BACKGROUND: Although antibiotic prophylaxis with levofloxacin can reduce the risk of serious infection in immunocompromised patients, the potential contribution of prophylaxis to antibiotic resistance is a major drawback. We aimed to identify the effects of levofloxacin prophylaxis, given to paediat...
Autores principales: | Margolis, Elisa B, Hakim, Hana, Dallas, Ronald H, Allison, Kim J, Ferrolino, Jose, Sun, Yilun, Pui, Ching-Hon, Yao, Jiangwei, Chang, Ti-Cheng, Hayden, Randall T, Jeha, Sima, Tuomanen, Elaine I, Tang, Li, Rosch, Jason W, Wolf, Joshua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336918/ https://www.ncbi.nlm.nih.gov/pubmed/34355208 http://dx.doi.org/10.1016/s2666-5247(20)30202-0 |
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