Folding non-homologous proteins by coupling deep-learning contact maps with I-TASSER assembly simulations

Structure prediction for proteins lacking homologous templates in the Protein Data Bank (PDB) remains a significant unsolved problem. We developed a protocol, C-I-TASSER, to integrate interresidue contact maps from deep neural-network learning with the cutting-edge I-TASSER fragment assembly simulat...

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Detalles Bibliográficos
Autores principales: Zheng, Wei, Zhang, Chengxin, Li, Yang, Pearce, Robin, Bell, Eric W., Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336924/
https://www.ncbi.nlm.nih.gov/pubmed/34355210
http://dx.doi.org/10.1016/j.crmeth.2021.100014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336924/
https://www.ncbi.nlm.nih.gov/pubmed/34355210
http://dx.doi.org/10.1016/j.crmeth.2021.100014

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