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The Optimal Cutoff Value of Z-scores Enhances the Judgment Accuracy of Noninvasive Prenatal Screening

OBJECTIVE: To evaluate the accuracy of Z-scores of noninvasive prenatal screening (NIPS) in predicting 21, 18 trisomy, and X chromosome aneuploidy. METHODS: A total of 39,310 prenatal women were recruited for NIPS from September 2015 to September 2020. Interventional prenatal diagnosis was applied t...

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Detalles Bibliográficos
Autores principales: Zhou, Lingna, Zhang, Bin, Liu, Jianbing, Shi, Ye, Wang, Jing, Yu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336938/
https://www.ncbi.nlm.nih.gov/pubmed/34367249
http://dx.doi.org/10.3389/fgene.2021.690063