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Self-assembling synthetic nanoadjuvant scaffolds cross-link B cell receptors and represent new platform technology for therapeutic antibody production

Host antibody responses are pivotal for providing protection against infectious agents. We have pioneered a new class of self-assembling micelles based on pentablock copolymers that enhance antibody responses while providing a low inflammatory environment compared to traditional adjuvants. This type...

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Detalles Bibliográficos
Autores principales: Senapati, Sujata, Darling, Ross J., Ross, Kathleen A., Wannemeuhler, Michael J., Narasimhan, Balaji, Mallapragada, Surya K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336949/
https://www.ncbi.nlm.nih.gov/pubmed/34348905
http://dx.doi.org/10.1126/sciadv.abj1691