Cargando…
Self-assembling synthetic nanoadjuvant scaffolds cross-link B cell receptors and represent new platform technology for therapeutic antibody production
Host antibody responses are pivotal for providing protection against infectious agents. We have pioneered a new class of self-assembling micelles based on pentablock copolymers that enhance antibody responses while providing a low inflammatory environment compared to traditional adjuvants. This type...
Autores principales: | Senapati, Sujata, Darling, Ross J., Ross, Kathleen A., Wannemeuhler, Michael J., Narasimhan, Balaji, Mallapragada, Surya K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336949/ https://www.ncbi.nlm.nih.gov/pubmed/34348905 http://dx.doi.org/10.1126/sciadv.abj1691 |
Ejemplares similares
-
Novel nanoadjuvants balance immune activation with modest inflammation: implications for older adult vaccines
por: Ross, Kathleen A., et al.
Publicado: (2023) -
Synthesis and Optimization of Next-Generation Low-Molecular-Weight Pentablock Copolymer Nanoadjuvants
por: Siddoway, Alaric C., et al.
Publicado: (2023) -
Rational Design of Pathogen-Mimicking Amphiphilic Materials as Nanoadjuvants
por: Ulery, Bret D., et al.
Publicado: (2011) -
Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8(+) T Cell Memory and Delayed Tumor Progression
por: Darling, Ross, et al.
Publicado: (2020) -
Respiratory nanoparticle-based vaccines and challenges associated with animal models and translation
por: Renukaradhya, Gourapura J., et al.
Publicado: (2015)