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Comparison of observation-based and model-based identification of alert concentrations from concentration–expression data

MOTIVATION: An important goal of concentration–response studies in toxicology is to determine an ‘alert’ concentration where a critical level of the response variable is exceeded. In a classical observation-based approach, only measured concentrations are considered as potential alert concentrations...

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Detalles Bibliográficos
Autores principales: Kappenberg, Franziska, Grinberg, Marianna, Jiang, Xiaoqi, Kopp-Schneider, Annette, Hengstler, Jan G, Rahnenführer, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337003/
https://www.ncbi.nlm.nih.gov/pubmed/33515236
http://dx.doi.org/10.1093/bioinformatics/btab043