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Comparison of observation-based and model-based identification of alert concentrations from concentration–expression data
MOTIVATION: An important goal of concentration–response studies in toxicology is to determine an ‘alert’ concentration where a critical level of the response variable is exceeded. In a classical observation-based approach, only measured concentrations are considered as potential alert concentrations...
Autores principales: | Kappenberg, Franziska, Grinberg, Marianna, Jiang, Xiaoqi, Kopp-Schneider, Annette, Hengstler, Jan G, Rahnenführer, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337003/ https://www.ncbi.nlm.nih.gov/pubmed/33515236 http://dx.doi.org/10.1093/bioinformatics/btab043 |
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