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McSplicer: a probabilistic model for estimating splice site usage from RNA-seq data

MOTIVATION: Alternative splicing removes intronic sequences from pre-mRNAs in alternative ways to produce different forms (isoforms) of mature mRNA. The composition of expressed transcripts gives specific functionalities to cells in a particular condition or developmental stage. In addition, a large...

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Detalles Bibliográficos
Autores principales: Alqassem, Israa, Sonthalia, Yash, Klitzke-Feser, Erika, Shim, Heejung, Canzar, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337008/
https://www.ncbi.nlm.nih.gov/pubmed/33515239
http://dx.doi.org/10.1093/bioinformatics/btab050