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McSplicer: a probabilistic model for estimating splice site usage from RNA-seq data
MOTIVATION: Alternative splicing removes intronic sequences from pre-mRNAs in alternative ways to produce different forms (isoforms) of mature mRNA. The composition of expressed transcripts gives specific functionalities to cells in a particular condition or developmental stage. In addition, a large...
Autores principales: | Alqassem, Israa, Sonthalia, Yash, Klitzke-Feser, Erika, Shim, Heejung, Canzar, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337008/ https://www.ncbi.nlm.nih.gov/pubmed/33515239 http://dx.doi.org/10.1093/bioinformatics/btab050 |
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