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The need for high-quality oocyte mitochondria at extreme ploidy dictates mammalian germline development
Selection against deleterious mitochondrial mutations is facilitated by germline processes, lowering the risk of genetic diseases. How selection works is disputed: experimental data are conflicting and previous modeling work has not clarified the issues; here, we develop computational and evolutiona...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337077/ https://www.ncbi.nlm.nih.gov/pubmed/34279226 http://dx.doi.org/10.7554/eLife.69344 |