Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer

Lineage transformation between lung cancer subtypes is a poorly understood phenomenon associated with resistance to treatment and poor patient outcomes. Here, we aimed to model this transition to define underlying biological mechanisms and identify potential avenues for therapeutic intervention. Sma...

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Detalles Bibliográficos
Autores principales: Inoue, Yusuke, Nikolic, Ana, Farnsworth, Dylan, Shi, Rocky, Johnson, Fraser D, Liu, Alvin, Ladanyi, Marc, Somwar, Romel, Gallo, Marco, Lockwood, William W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337080/
https://www.ncbi.nlm.nih.gov/pubmed/34121659
http://dx.doi.org/10.7554/eLife.66524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337080/
https://www.ncbi.nlm.nih.gov/pubmed/34121659
http://dx.doi.org/10.7554/eLife.66524

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