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Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
Lineage transformation between lung cancer subtypes is a poorly understood phenomenon associated with resistance to treatment and poor patient outcomes. Here, we aimed to model this transition to define underlying biological mechanisms and identify potential avenues for therapeutic intervention. Sma...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337080/ https://www.ncbi.nlm.nih.gov/pubmed/34121659 http://dx.doi.org/10.7554/eLife.66524 |