Cargando…

Topological defects in the mesothelium suppress ovarian cancer cell clearance

We investigated an in vitro model for mesothelial clearance, wherein ovarian cancer cells invade into a layer of mesothelial cells, resulting in mesothelial retraction combined with cancer cell disaggregation and spreading. Prior to the addition of tumor cells, the mesothelial cells had an elongated...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jun, Yang, Ning, Kreeger, Pamela K., Notbohm, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337086/
https://www.ncbi.nlm.nih.gov/pubmed/34396026
http://dx.doi.org/10.1063/5.0047523