Advanced Oxidation Protein Products Induce G1/G0-Phase Arrest in Ovarian Granulosa Cells via the ROS-JNK/p38 MAPK-p21 Pathway in Premature Ovarian Insufficiency

The mechanism underlying the role of oxidative stress and advanced oxidation protein products (AOPPs) in the aetiology of premature ovarian insufficiency (POI) is poorly understood. Here, we investigated the plasma AOPP level in POI patients and the effects of AOPPs on granulosa cells both in vitro...

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Detalles Bibliográficos
Autores principales: Zhou, Xing-Yu, Zhang, Jun, Li, Ying, Chen, Ying-Xue, Wu, Xiao-Min, Li, Xin, Zhang, Xiao-Fei, Ma, Lin-Zi, Yang, Yi-Zhen, Zheng, Ke-Ming, Liu, Yu-Dong, Wang, Zhe, Chen, Shi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337115/
https://www.ncbi.nlm.nih.gov/pubmed/34367464
http://dx.doi.org/10.1155/2021/6634718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337115/
https://www.ncbi.nlm.nih.gov/pubmed/34367464
http://dx.doi.org/10.1155/2021/6634718

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