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Inverse Agonist of Retinoid-Related Orphan Receptor-Alpha Prevents Apoptosis and Degeneration in Nucleus Pulposus Cells via Upregulation of YAP

Intervertebral disc degenerative disease (IDD) is the most common degenerative spine disease, which leads to chronic low back pain and symptoms in the lower extremities. In this study, we found that RORα, a member of the retinoid-related orphan receptor family, is significantly elevated in nucleus p...

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Detalles Bibliográficos
Autores principales: Liang, Tongzhou, Qiu, Jincheng, Li, Shaoguang, Deng, Zhihuai, Qiu, Xianjian, Hu, Wenjun, Li, Pengfei, Chen, Taiqiu, Liang, Zhancheng, Zhou, Hang, Gao, Bo, Huang, Dongsheng, Liang, Anjing, Gao, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337132/
https://www.ncbi.nlm.nih.gov/pubmed/34366712
http://dx.doi.org/10.1155/2021/9954909