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Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics
Alzheimer’s disease (AD) is defined by the presence of abundant amyloid-β (Aβ) and tau neuropathology. While this neuropathology is necessary for AD diagnosis, it is not sufficient for causing cognitive impairment. Up to one third of community dwelling older adults harbor intermediate to high levels...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338777/ https://www.ncbi.nlm.nih.gov/pubmed/34052751 http://dx.doi.org/10.1016/j.neurobiolaging.2021.04.012 |