Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics

Alzheimer’s disease (AD) is defined by the presence of abundant amyloid-β (Aβ) and tau neuropathology. While this neuropathology is necessary for AD diagnosis, it is not sufficient for causing cognitive impairment. Up to one third of community dwelling older adults harbor intermediate to high levels...

Descripción completa

Detalles Bibliográficos
Autores principales: Carlyle, Becky C., Kandigian, Savannah E., Kreuzer, Johannes, Das, Sudeshna, Trombetta, Bianca A., Kuo, Yikai, Bennett, David A., Schneider, Julie A., Petyuk, Vladislav A., Kitchen, Robert R., Morris, Robert, Nairn, Angus C., Hyman, Bradley T., Haas, Wilhelm, Arnold, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338777/
https://www.ncbi.nlm.nih.gov/pubmed/34052751
http://dx.doi.org/10.1016/j.neurobiolaging.2021.04.012

Ejemplares similares

Ejemplares similares