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Local Anti–PD-1 Delivery Prevents Progression of Premalignant Lesions in a 4NQO-Oral Carcinogenesis Mouse Model

Although the principle of systemic treatment to prevent the progression of oral premalignant lesions (OPL) has been demonstrated, there remains a lack of consensus about an optimal approach that balances clinical efficacy with toxicity concerns. Recent advances in cancer therapy using approaches tar...

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Detalles Bibliográficos
Autores principales: Shi, Yewen, Xie, Tong-xin, Leach, David G., Wang, Bingbing, Young, Simon, Osman, Abdullah A., Sikora, Andrew G., Ren, Xiaoyong, Hartgerink, Jeffrey D., Myers, Jeffrey N., Rangel, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338806/
https://www.ncbi.nlm.nih.gov/pubmed/34021022
http://dx.doi.org/10.1158/1940-6207.CAPR-20-0607