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Gene Fusions Create Partner and Collateral Dependencies Essential to Cancer Cell Survival

Gene fusions frequently result from rearrangements in cancer genomes. In many instances, gene fusions play an important role in oncogenesis; in other instances, they are thought to be passenger events. Although regulatory element rearrangements and copy number alterations resulting from these struct...

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Detalles Bibliográficos
Autores principales: Gillani, Riaz, Seong, Bo Kyung A., Crowdis, Jett, Conway, Jake R., Dharia, Neekesh V., Alimohamed, Saif, Haas, Brian J., Han, Kyuho, Park, Jihye, Dietlein, Felix, He, Meng Xiao, Imamovic, Alma, Ma, Clement, Bassik, Michael C., Boehm, Jesse S., Vazquez, Francisca, Gusev, Alexander, Liu, David, Janeway, Katherine A., McFarland, James M., Stegmaier, Kimberly, Van Allen, Eliezer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338889/
https://www.ncbi.nlm.nih.gov/pubmed/34099491
http://dx.doi.org/10.1158/0008-5472.CAN-21-0791