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GATA3 maintains the quiescent state of cochlear supporting cells by regulating p27(kip1)

Haplo-insufficiency of the GATA3 gene causes hypoparathyroidism, sensorineural hearing loss, and renal disease (HDR) syndrome. Previous studies have shown that Gata3 is required for the development of the prosensory domain and spiral ganglion neurons (SGNs) of the mouse cochlea during embryogenesis....

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Detalles Bibliográficos
Autores principales: Xu, Jiadong, Yu, Dongliang, Dong, Xuhui, Xie, Xiaoling, Xu, Mei, Guo, Luming, Huang, Liang, Tang, Qi, Gan, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338922/
https://www.ncbi.nlm.nih.gov/pubmed/34349220
http://dx.doi.org/10.1038/s41598-021-95427-3