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GATA3 maintains the quiescent state of cochlear supporting cells by regulating p27(kip1)
Haplo-insufficiency of the GATA3 gene causes hypoparathyroidism, sensorineural hearing loss, and renal disease (HDR) syndrome. Previous studies have shown that Gata3 is required for the development of the prosensory domain and spiral ganglion neurons (SGNs) of the mouse cochlea during embryogenesis....
Autores principales: | Xu, Jiadong, Yu, Dongliang, Dong, Xuhui, Xie, Xiaoling, Xu, Mei, Guo, Luming, Huang, Liang, Tang, Qi, Gan, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338922/ https://www.ncbi.nlm.nih.gov/pubmed/34349220 http://dx.doi.org/10.1038/s41598-021-95427-3 |
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