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Effects of high rosuvastatin doses on hepatocyte mitochondria of hypercholesterolemic mice

Statins are the cornerstone of therapy for individuals with hyperlipidemia. The aim of this study was to analyze the undesirable effects of mild, moderate and high doses of rosuvastatin in CD-1 male mice who received a cholesterol-rich diet, focusing on the morphological and functional changes on he...

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Detalles Bibliográficos
Autores principales: Díaz-Zagoya, Juan C., Marín-Medina, Alejandro, Zetina-Esquivel, Alma M., Blé-Castillo, Jorge L., Castell-Rodríguez, Andrés E., Juárez-Rojop, Isela E., Miranda-Zamora, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338935/
https://www.ncbi.nlm.nih.gov/pubmed/34349148
http://dx.doi.org/10.1038/s41598-021-95140-1