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Effects of high rosuvastatin doses on hepatocyte mitochondria of hypercholesterolemic mice
Statins are the cornerstone of therapy for individuals with hyperlipidemia. The aim of this study was to analyze the undesirable effects of mild, moderate and high doses of rosuvastatin in CD-1 male mice who received a cholesterol-rich diet, focusing on the morphological and functional changes on he...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338935/ https://www.ncbi.nlm.nih.gov/pubmed/34349148 http://dx.doi.org/10.1038/s41598-021-95140-1 |