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Simvastatin therapy attenuates memory deficits that associate with brain monocyte infiltration in chronic hypercholesterolemia

Evidence associates cardiovascular risk factors with unfavorable systemic and neuro-inflammation and cognitive decline in the elderly. Cardiovascular therapeutics (e.g., statins and anti-hypertensives) possess immune-modulatory functions in parallel to their cholesterol- or blood pressure (BP)-lower...

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Detalles Bibliográficos
Autores principales: Don-Doncow, Nicholas, Vanherle, Lotte, Matthes, Frank, Petersen, Sine Kragh, Matuskova, Hana, Rattik, Sara, Härtlova, Anetta, Meissner, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338939/
https://www.ncbi.nlm.nih.gov/pubmed/34349106
http://dx.doi.org/10.1038/s41514-021-00071-w