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Berberine elevates cardiolipin in heart of offspring from mouse dams with high fat diet-induced gestational diabetes mellitus

Berberine (BBR) is an isoquinoline alkaloid from plants known to improve cardiac mitochondrial function in gestational diabetes mellitus (GDM) offspring but the mechanism is poorly understood. We examined the role of the mitochondrial phospholipid cardiolipin (CL) in mediating this cardiac improveme...

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Detalles Bibliográficos
Autores principales: Cole, Laura K., Sparagna, Genevieve C., Vandel, Marilyne, Xiang, Bo, Dolinsky, Vernon W., Hatch, Grant M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338981/
https://www.ncbi.nlm.nih.gov/pubmed/34349203
http://dx.doi.org/10.1038/s41598-021-95353-4