Vertically transferred maternal immune cells promote neonatal immunity against early life infections

During mammalian pregnancy, immune cells are vertically transferred from mother to fetus. The functional role of these maternal microchimeric cells (MMc) in the offspring is mostly unknown. Here we show a mouse model in which MMc numbers are either normal or low, which enables functional assessment...

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Detalles Bibliográficos
Autores principales: Stelzer, Ina Annelies, Urbschat, Christopher, Schepanski, Steven, Thiele, Kristin, Triviai, Ioanna, Wieczorek, Agnes, Alawi, Malik, Ohnezeit, Denise, Kottlau, Julian, Huang, Jiabin, Fischer, Nicole, Mittrücker, Hans-Willi, Solano, Maria Emilia, Fehse, Boris, Diemert, Anke, Stahl, Felix R., Arck, Petra Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338998/
https://www.ncbi.nlm.nih.gov/pubmed/34349112
http://dx.doi.org/10.1038/s41467-021-24719-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338998/
https://www.ncbi.nlm.nih.gov/pubmed/34349112
http://dx.doi.org/10.1038/s41467-021-24719-z

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