Co-culture model of B-cell acute lymphoblastic leukemia recapitulates a transcription signature of chemotherapy-refractory minimal residual disease

B-cell acute lymphoblastic leukemia (ALL) is characterized by accumulation of immature hematopoietic cells in the bone marrow, a well-established sanctuary site for leukemic cell survival during treatment. While standard of care treatment results in remission in most patients, a small population of...

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Detalles Bibliográficos
Autores principales: Rellick, Stephanie L., Hu, Gangqing, Piktel, Debra, Martin, Karen H., Geldenhuys, Werner J., Nair, Rajesh R., Gibson, Laura F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339057/
https://www.ncbi.nlm.nih.gov/pubmed/34349149
http://dx.doi.org/10.1038/s41598-021-95039-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339057/
https://www.ncbi.nlm.nih.gov/pubmed/34349149
http://dx.doi.org/10.1038/s41598-021-95039-x

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