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Efficacy and Safety of Peripherally Acting μ-Opioid Receptor Antagonist (PAMORAs) for the Management of Patients With Opioid-Induced Constipation: A Systematic Review

In treating chronic and acute pain, opioids are widely used. Although they do provide analgesia, their usage does come with adverse events (AEs). One of the most burdensome is opioid-induced bowel dysfunction, and more specifically opioid-induced constipation (OIC). The pathogenesis of these AEs is...

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Detalles Bibliográficos
Autores principales: Rekatsina, Martina, Paladini, Antonella, Drewes, Asbjørn M, Ayob, Farrah, Viswanath, Omar, Urits, Ivan, Corli, Oscar, Pergolizzi Jr, Joseph, Varrassi, Giustino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339109/
https://www.ncbi.nlm.nih.gov/pubmed/34367804
http://dx.doi.org/10.7759/cureus.16201