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Agonist dependency of the second phase access of β-arrestin 2 to the heteromeric µ-V1b receptor
During the development of analgesic tolerance to morphine, the V1b vasopressin receptor has been proposed to bind to β-arrestin 2 and the µ-opioid receptor to enable their interaction. However, direct evidence of such a high-order complex is lacking. Using bioluminescent resonance energy transfer be...
Autores principales: | Ngamlertwong, Nuttawadee, Tsuchiya, Hiroyoshi, Mochimaru, Yuta, Azuma, Morio, Kuchimaru, Takahiro, Koshimizu, Taka-aki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339129/ https://www.ncbi.nlm.nih.gov/pubmed/34349143 http://dx.doi.org/10.1038/s41598-021-94894-y |
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