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TGF-β1 facilitates MT1-MMP-mediated proMMP-9 activation and invasion in oral squamous cell carcinoma cells

Matrix metalloproteinase (MMP)-2 and MMP-9, also known as gelatinases or type IV collagenases, are recognized as major contributors to the proteolytic degradation of extracellular matrix during tumor invasion. Latent MMP-2 (proMMP-2) is activated by membrane type 1 MMP (MT1-MMP) on the cell surface...

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Detalles Bibliográficos
Autores principales: Yamahana, Hirari, Terashima, Minoru, Takatsuka, Risa, Asada, Chikako, Suzuki, Takeshi, Uto, Yoshihiro, Takino, Takahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339144/
https://www.ncbi.nlm.nih.gov/pubmed/34381878
http://dx.doi.org/10.1016/j.bbrep.2021.101072