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Structure of the Mycobacterium tuberculosis cPknF and conformational changes induced in forkhead-associated regulatory domains

Mycobacterium tuberculosis (Mtb) has 11 Serine-Threonine Protein Kinases (STPK) that control numerous physiological processes, including cell growth, cell division, metabolic flow, and transcription. PknF is one of the 11 Mtb STPKs that has, among other substrates, two FHA domains (FHA-1 and FHA-2)...

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Detalles Bibliográficos
Autores principales: Cabarca, Sindy, Frazão de Souza, Maximilia, Albert de Oliveira, Andrew, Vignoli Muniz, Gabriel S., Lamy, M. Teresa, Vinicius dos Reis, Caio, Takarada, Jessica, Effer, Brian, Souza, Lucas Santos, Iriarte de la Torre, Lilia, Couñago, Rafael, Pinto Oliveira, Cristiano Luis, Balan, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339232/
https://www.ncbi.nlm.nih.gov/pubmed/34382010
http://dx.doi.org/10.1016/j.crstbi.2021.07.001