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Protocol for executing and benchmarking eight computational doublet-detection methods in single-cell RNA sequencing data analysis

The existence of doublets is a key confounder in single-cell RNA sequencing (scRNA-seq) data analysis. Computational techniques have been developed for detecting doublets from scRNA-seq data. We developed an R package DoubletCollection to integrate the installation and execution of eight doublet det...

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Detalles Bibliográficos
Autores principales: Xi, Nan Miles, Li, Jingyi Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339294/
https://www.ncbi.nlm.nih.gov/pubmed/34382023
http://dx.doi.org/10.1016/j.xpro.2021.100699