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Generating Chromosome Geometries in a Minimal Cell From Cryo-Electron Tomograms and Chromosome Conformation Capture Maps

JCVI-syn3A is a genetically minimal bacterial cell, consisting of 493 genes and only a single 543 kbp circular chromosome. Syn3A’s genome and physical size are approximately one-tenth those of the model bacterial organism Escherichia coli’s, and the corresponding reduction in complexity and scale pr...

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Detalles Bibliográficos
Autores principales: Gilbert, Benjamin R., Thornburg, Zane R., Lam, Vinson, Rashid, Fatema-Zahra M., Glass, John I., Villa, Elizabeth, Dame, Remus T., Luthey-Schulten, Zaida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339304/
https://www.ncbi.nlm.nih.gov/pubmed/34368224
http://dx.doi.org/10.3389/fmolb.2021.644133