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Regulation of nonsense-mediated mRNA decay in neural development and disease

Eukaryotes have evolved a variety of mRNA surveillance mechanisms to detect and degrade aberrant mRNAs with potential deleterious outcomes. Among them, nonsense-mediated mRNA decay (NMD) functions not only as a quality control mechanism targeting aberrant mRNAs containing a premature termination cod...

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Detalles Bibliográficos
Autores principales: Lee, Paul Jongseo, Yang, Suzhou, Sun, Yu, Guo, Junjie U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339359/
https://www.ncbi.nlm.nih.gov/pubmed/33783512
http://dx.doi.org/10.1093/jmcb/mjab022