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Whole genome sequencing of low input circulating cell‐free DNA obtained from normal human subjects

Cell‐free DNA circulates in plasma at low levels as a normal by‐product of cellular apoptosis. Multiple clinical pathologies, as well as environmental stressors can lead to increased circulating cell‐free DNA (ccfDNA) levels. Plasma DNA studies frequently employ targeted amplicon deep sequencing pla...

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Detalles Bibliográficos
Autores principales: Foley, Julie F., Elgart, Brian, Alex Merrick, B., Phadke, Dhiral P., Cook, Molly E., Malphurs, Jason A., Solomon, Gregory G., Shah, Ruchir R., Fessler, Michael B., Miller, Frederick W., Gerrish, Kevin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339531/
https://www.ncbi.nlm.nih.gov/pubmed/34350716
http://dx.doi.org/10.14814/phy2.14993