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Normalization of non‐canonical Wnt signalings does not compromise blood‐brain barrier protection conferred by upregulating endothelial Wnt/β‐catenin signaling following ischemic stroke

BACKGROUND: Endothelial canonical (Wnt/β‐catenin) and non‐canonical Wnt signalings (Wnt/PCP and Wnt/Ca(2+)) promote blood‐brain barrier (BBB) development and antagonize each other. However, the effects of ischemic stroke on endothelial canonical and non‐canonical Wnt signalings are unclear. Further,...

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Detalles Bibliográficos
Autores principales: Ji, Ya‐bin, Wang, Tian‐xi, Gao, Qiang, Huang, Xiao‐wen, Chang, Junlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339534/
https://www.ncbi.nlm.nih.gov/pubmed/34056869
http://dx.doi.org/10.1111/cns.13661