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TIGIT, the Next Step Towards Successful Combination Immune Checkpoint Therapy in Cancer

T cell immunoreceptor with Ig and ITIM domains (TIGIT) is an inhibitory receptor expressed on several types of lymphocytes. Efficacy of antibody blockade of TIGIT in cancer immunotherapy is currently widely being investigated in both pre-clinical and clinical studies. In multiple cancers TIGIT is ex...

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Detalles Bibliográficos
Autores principales: Ge, Zhouhong, Peppelenbosch, Maikel P., Sprengers, Dave, Kwekkeboom, Jaap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339559/
https://www.ncbi.nlm.nih.gov/pubmed/34367161
http://dx.doi.org/10.3389/fimmu.2021.699895